Dallas Team Seeks Participants for Breast Cancer Treatment Study

Researchers at UT Southwestern Medical Center in Dallas are currently conducting a clinical trial that may offer a new treatment avenue for certain breast cancer patients. The trial, still in progress, particularly seeks women diagnosed with early-stage, operable, hormone-positive breast cancer.

The research, led by radiation oncologist Asal Rahimi, is advancing into Phase II following promising outcomes from initial studies. Notably, findings published in JAMA Network Open in November 2025 suggest a potential paradigm shift in managing the most prevalent form of breast cancer, traditionally treated with surgery followed by radiation therapy.

Rahimi noted that in 72% of participants, tumors were completely eradicated, while another 21% saw more than 90% reduction in cancer. Pam Minick, an Argyle resident and 2026 Miss Rodeo America Hall of Fame inductee, who received a single high dose of radiation prior to surgery, shared her positive results, stating, “All the biopsy tissue was negative for cancer.” The study, funded by a grant from the Cancer Prevention and Research Institute of Texas (CPRIT), is actively recruiting patients.